Collinearity of protease mutations in HIV-1 samples with high-level protease inhibitor class resistance
نویسندگان
چکیده
منابع مشابه
Collinearity of protease mutations in HIV-1 samples with high-level protease inhibitor class resistance
OBJECTIVES To determine whether pan-protease inhibitor (PI)-resistant virus populations are composed predominantly of viruses with resistance to all PIs or of diverse virus populations with resistance to different subsets of PIs. METHODS We performed deep sequencing of plasma virus samples from nine patients with high-level genotypic and/or phenotypic resistance to all licensed PIs. The nine ...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2012
ISSN: 1460-2091,0305-7453
DOI: 10.1093/jac/dks409